Les chercheurs de l’Unité sont reconnus mondialement et fréquemment invités comme conférenciers, tant à l’échelle nationale qu’internationale, afin de présenter leurs travaux et/ou à discuter des traitements ainsi que des nouvelles approches thérapeutiques reliées à cette maladie. De plus, des prix d’excellence de renommée internationale ont été décernés à plusieurs chercheurs de l’Unité pour la qualité et l’originalité de leurs travaux.

Voici une courte liste de publications récentes et pertinentes.


  1. Roubille, C., Martel-Pelletier, J., Pelletier, J.P.: Osteoarthritis treatments: where do we stand at the moment? Medicographia 35(2):172-180, 2013.

Chapitres de livre et Revues

  1. Roubille, C., Pelletier, J.P., Martel-Pelletier, J.: Drug/Agent Treatments for Osteoarthritis – Present and Future. In: Osteoarthritis: Pathogenesis, diagnosis, available treatments, drug safety, regenerative and personalized medicine. Kapoor, M. et Mahomed, N.N., eds. Springer. New York, NY, É.-U. Chapitre 10, pp 191-210, 2015.

Articles scientifiques

  1. Pelletier, J.P., Dorais, M., Paiement, P., Raynauld, J.P., Martel-Pelletier, J.: Risk factors associated with the occurrence of total knee arthroplasty in patients with knee osteoarthritis: A nested case-control study. Adv. Musculoskelet. Dis. 14:1759720X221091359. doi: 10.1177/1759720X221091359, 2022.
  2. Bonakdari, H., Pelletier, J.P., Abram, F., Martel-Pelletier, J.: A machine learning model to predict knee osteoarthritis cartilage volume changes over time using baseline bone curvature. Biomedicines 10:1247, 2022 doi.org/10.3390/biomedicines10061247.
  3. Martel-Pelletier, J., Tardif, G., Paiement, P., Pelletier, J.P.: Common biochemical and magnetic resonance imaging biomarkers of early knee osteoarthritis and of exercise/training in athletes. A narrative review. Diagnostics (Special Issue: Biomarkers in OA) 11:1488, 2021. https://doi.org/10.3390.diagnostics1081488.
  4. Jamshidi, A., Pelletier, J.P., Labbe. , Abram, F., Martel-Pelletier, J.*, Droit, A.*: Machine learning-based individualized survival prediction model for total knee replacement in osteoarthritis: Data from the Osteoarthritis Initiative. Arthritis Care & Res. 73 (10):1518-1527, 2021. doi.org/10.1002/acr.24601.
  5. Wang, Y., Martel-Pelletier, J., Teichtahl, A.J., Wluka, A.E., Hussain, S.M., Pelletier, J.P., Cicuttini, F.M.: The bulge sign – a simple physical examination for identifying progressive knee osteoarthritis: data from the Osteoarthritis Initiative. Rheumatology (Oxford) doi/10.1093/rheumatology/kez443.
  6. Bonakdari, H., Jamshidi, A., Pelletier, J.P., Abram, F., Tardif, G., Martel-Pelletier, J.: A warning machine learning tool for early knee osteoarthritis structural progressor patient screening: Making headway on precision medicine. Adv. Musculoskel. Dis. 13:1-16, 2021. doi :10.1177/1759720X21993254.
  7. Bonakdari, H., Tardif, G., Abram, F, Pelletier, J.P., Martel-Pelletier, J.: Serum adipokines/related inflammatory factors and ratios as predictors of infrapatellar fat pad volume in osteoarthritis: Applying comprehensive machine learning approaches. Rep. 10, 9993 (2020). doi.org/10.1038/s41598-020-66330-0.
  8. Pelletier, J.P., Raynauld, J.P., Abram, F., Dorais, M., Paiement, P., Martel-Pelletier, J.: Intra-articular corticosteroid knee injection induces a reduction in meniscal thickness with no treatment effect on cartilage volume: A case-control study. Rep. 10(1):13789, 2020. doi.org/10.1038/s41598-020-70064-4.
  9. Bonakdari, H., Pelletier, J.P., Martel-Pelletier, J.: Viewpoint on time series and interrupted time series optimum modelling for predicting arthritic disease outcome. Rheum. Rep. 22:27, 2020.
  10. Bonakdari, H., Pelletier, J.P., Martel-Pelletier, J.: A reliable time-series method for predicting arthritic disease outcomes: new step from regression toward a nonlinear artificial intelligence method. Methods Programs Biomed. 189:105315, 2020.
  11. Jamshidi, A., Leclercq, M., Labbe, A., Pelletier, J.P., Abram, F., Droit, A., Martel-Pelletier, J.: Identification of the most important features of knee osteoarthritis structural progressors using machine learning methods. Adv. Musculoskelet. Dis. 12:1-12, 2020. doi: 10.1177/1759720X20933468.
  12. Fuggle, N.R., Cooper, C., Oreffo, R., Price, A., Kaux, J.F., Maheu, E., Cutolo, M., Honvo, G., Laslop, A., Conaghan, P., Berenbaum, F., Branco, J., Brandi, M.L., Cortet, B., Veronese, N., Kurth, A.A. Radmilam, N.S., Roth, R., Pelletier, J.P., Martel-Pelletier, J., Vlaskovska, M., Thomas, T., Lems, W.F., Bruyere, O., Rizzoli, R., Kanis, J.A., Reginster, J.Y.: Alternative and complementary therapies in osteoarthritis and cartilage repair. Aging Clin. Exp. Res. 32(4): 547-560, 2020.
  13. Cai, G., Aitken, D., Laslett, L.L., Pelletier, J.P., Martel-Pelletier, J., Hill, C., March, L., Wluka, A.E., Wang, Y., Antony, B., Blizzard, L., Winzenberg, T., Cicuttini, F., Jones, G.: Effect of intravenous zoledronic acid on tibiofemoral cartilage volume among patients with knee osteoarthritis with bone marrow lesions: A randomized clinical trial. JAMA 323(15):1456-1466, 2020.
  14. Pelletier, J.P., Raynauld, J.P., Dorais, M., Bessette, L., Dokoupilova, E., Morin, F., Pavelka, K., Martel-Pelletier, J. for the DISSCO Trial Investigator Group. An international, multicentre, double-blind, randomised study (DISSCO): effect of diacerein vs celecoxib on symptoms in knee osteoarthritis. Rheumatology (Oxford) 59(12):3858-3868, 2020.
  15. Bruyère, O., Honvo, G., Veronese, N., Arden, N.K., Branco, J., Curtis, E.M., Al-Daghri, N.M., Herrero-Beaumont, G., Martel-Pelletier, J., Pelletier, J.P., Rannou, F., Rizzoli, R., Roth, R., Uebelhart, D., Cooper, C., Reginster, J.Y.: An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Arthritis Rheum. 49(3):337-350, 2019.
  16. Martel-Pelletier, J., Maheu, E., Pelletier, J.P., Alekseeva, L., Mkinsi, O., Branco, J., Monod, P., Planta, F., Reginster, J.Y., Rannou, F.: A new decision tree for diagnosis of osteoarthritis in primary care: international consensus of experts. Aging Clin. Exp. Res. 31(1):19-30, 2019.
  17. Fleischmann, R.M., Bliddal, H., Blanco, F.J., Schnitzer, T.J., Peterfy, C., Chen, S., Wang, L., Feng, S., Conaghan, P.G., Berenbaum, F., Pelletier, J.P., Martel-Pelletier, J., Vaeterlein, O., Kaeley, G.S., Liu, W., Kosloski, M.P., Levy, G., Zhang, L., Medema, J.K., Levesque, M.C.: A phase II trial of lutikizumab, an anti-interleukin 1α/β dual variable domain immunoglobulin, in knee osteoarthritis patients with synovitis. Arthritis Rheumatol. 71(7):1056-1069, 2019.
  18. Jamshidi, A., Pelletier, J.P., Martel-Pelletier, J.: Machine-learning-based patient-specific prediction models for knee osteoarthritis. Rev. Rheumatol. 15(1):49-60, 2019.
  19. Dorais, M., Martel-Pelletier, J., Raynauld, J.P., Delorme, P., Pelletier, J.P.: Impact of oral osteoarthritis therapeutics usage among other risk factors on total knee replacement: a nested case-control study using the Osteoarthritis Initiative cohort. Arthritis Res. & Ther. 20(1):172, 2018.
  20. Pelletier, J.P., Raynauld, J.P., Abram, F., Dorais, M., Delorme, P., Martel-Pelletier, J.: Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative. Arthritis Res. Ther. 20(1):40, 2018.
  21. Bhandari, M., Bannuru, R.R., Babins, E.M., Martel-Pelletier, J., Khan, M., Raynauld, J.P., Frankovich, R., McLeod, D., Devji, T., Phillips, M., Schemitsch, E.H., Pelletier, J.P.: Intra-articular hyaluronic acid in the treatment of knee osteoarthritis – A Canadian evidence-based perspective. Adv. in Musculoskelet. Dis. 9(9):231-246, 2017.
  22. Martel-Pelletier, J., Raynauld, J.P., Mineau, F., Abram, F., Paiement, P., Delorme, P., Pelletier, J.P.: Levels of serum biomarkers from a two-year multicentre trial are associated with treatment response on knee osteoarthritis cartilage loss as assessed by magnetic resonance imaging: an exploratory study. Arthritis Res. Ther. 19(1):169, 2017.
  23. Pelletier, J.P., Raynauld, J.P., Beaulieu, A., Bessette, L., Morin, F., de Brum-Fernandes, A.J., Delorme, P., Dorais, M., Paiement, P., Abram, F., Martel-Pelletier, J.: Chondroitin sulfate efficacy versus celecoxib on knee osteoarthritis structural changes using magnetic resonance imaging: a 2-year multicenter exploratory study. Arthritis Res. Ther. 18(1):256, 2016.
  24. Martel-Pelletier, J., Barr, A.J., Cicuttini, F.M., Conaghan, P.G., Cooper, C., Goldring, M.B., Goldring, S.R., Jones, G., Teichtahl, A.J., Pelletier, J.P.: Osteoarthritis. Rev. Dis. Prim. 2:16072, 2016. (Mention spéciale pour cet article en 2019 par Web of Science).